Article Details

Analgesic and Anti-inflammatory Activity of Methanolic Extract from Jatropha Curcas (Euphorbiaceae)Leaves on Experimental Animals

Chandra P.*, Sachan N., Yadav R., Kishore K. and Ghosh A. K.


ABSTRACT

The present study evaluates the analgesic and anti-inflammatory activities of the methanolic extractfrom Jatropha curcas (Euphorbiaceae) leaves to provide experimental evidence for its traditional use.Investigations on the analgesic effects and anti-inflammatory activities of J. curcas were carried outby utilizing the different animal models. It has been shown that the methanolic extract from Jatrophacurcas leaves significantly increased pain threshold and reduced writhing response as well as inhibitedthe increase in vascular permeability. Also, it significantly decreased the carrageenan-induced rat pawedema. The results show that the methanolic extract from Jatropha curcas leaves have both central andperipheral analgesic activities and as anti-inflammatory effects, supporting the traditional application ofthis herb in treating various diseases associated with inflammation and pain.
Year 2013 | Volume No. 50 | Issue No.8 | Page No. 32
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