Article Details

ANTI-TUBERCULAR ACTIVITY OF SYNTHESIZED NOVEL 2,5-DISUBSTITUTED-1,3,4-OXADIAZOLE DERIVATIVES

Ega D., Attari Z., Mudgal J., Bairy I., Vishnuprasad S. and Nampurath G. K.*

Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal - 576 104, Karnataka, India.

 

*E-mail: ng.kutty@manipal.edu

 

https://doi.org/10.53879/id.52.02.10107


ABSTRACT

A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

Year 2015 | Volume No. 52 | Issue No.02 | Page No. 40-44
Recent Issue
Current Issue
June 2025
Quick Contact