Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal - 576 104, Karnataka, India.
*E-mail: ng.kutty@manipal.edu
https://doi.org/10.53879/id.52.02.10107
ABSTRACT
A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.