Mucoadhesive polymers are the topic of current interest in the design of drug delivery systems. Mucoadhesive microspheres provide the means of improving drug delivery by promoting the residence time at the site of application or absorption and facilitate intimate contact with the underlying absor...

Millions of people are affected by infectious diseases caused by micro-organisms. Further the widespread microbial resistance had renewed the interest in quest for new antitubercular, antimicrobial & antifungal agents. The present study deals with synthesis & evaluation of some substitute...

Study was undertaken with an objective to develop a simple method for isolation of ursolic acid from Nerium indicum Mill leaves and to prepare synthetic derivatives of ursolic acid. The leaves were defatted with petroleum ether and then extracted with methanol. Methanol extract was basified and s...

From the petroleum ether extract of flowers, betulin, friedelin and lupeol were isolated for the first time along with six other known compounds viz. n-triacontane, ester of beta-sitosterol, tricosyl alcohol, taraxasterol, beta-amyrin etc. During antibacterial screening, water extract of seeds sh...

Stable sustained release tablets of levofloxacin hemihydrate were successfully prepared by wet granulation technique. Compatible excipients were selected and different formulations were prepared with varying proportion and grades of hydroxy propyl methyl cellulose. Tablets were prepared by compre...

A simple, specific, accurate and precise reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of olmesartan medoxomil and metoprolol succinate in tablet dosage form. A Phenomenex-C18, 5 mcm column 250 mm 4.6 mm in gradient mode, with mobile ph...

A reverse phase high performance liquid chromatographic method is developed for the simultaneous determination of metformin hydrochloride and repaglinide. Chromatography was carried out at ambient temperature and separation of these drugs was achieved on neosphere C18 column (150 x 4.6 mm i.d, 3....