Table of Contents

February  2015

  • Volume 52
  • Issue 02
  • Page Nos. 48

Review Article

QUALITY BY DESIGN: AN OVERVIEW

PAGE 5-11
Quality by Design (QbD) is a systematic, scientific, holistic and proactive approach that begins with pre-defined objectives and emphasis on product, process understanding and process control. It essentially necessitates designing and developing the product and the manufacturing process to achieve...
Suresh S*., Roy S., Ahuja B. K.

Original Research Articles

HPTLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF STIGMASTEROL AND β-SITOSTEROL IN ABROMA AUGUSTA LINN. ROOTS AND ITS IN VITRO BIOLOGICAL ACTIVITY SCREENING

PAGE 12-19
The intention of the present work is to quantify stigmasterol and β-sitosterol and simultaneously estimate them in the roots of Abroma augusta Linn. with the help of standard markers using HPTLC technique and to carry out the evaluation of their anti-arthritic and anti-gout activities. The finger...
Jayaprakasam R*., Philip N., Vinod S., Jacob L., Thengungal K. R.

QBD BASED RP-HPLC METHOD FOR SCREENING AND ANALYSIS OF TELAPRAVIR AND 7 OTHER ANTIRETROVIRAL AGENTS

PAGE 20-33
The present study describes the separation and simultaneous estimation of eight anti-retroviral drugs, namely, Telaprevir (TPV), Emtricitabine (ECB), Fosamprenavir (FANV), Tenofavir (TNF), Ritonavir (RNV), Raltegravir (RGV) and Oseltamivir (OSMV) and Zidovudine (ZDV) as an active pharmaceutical i...
Kumar N. S*., Kumaraswamy R., Shantikumar S., Paul D.

FORCED DEGRADATION STUDY OF POST-SHELF LIFE AND MARKETED TABLETS OF AMLODIPINE BY RP-HPLC

PAGE 34-39
The stability of pharmaceutical products plays an important role from the economical point of view. There are not many studies that report about the stability of drugs past their expiration dates. The objective of the current study was to determine tablet content and perform dissolution test of ex...
Puranik M*., Yeole P. G. and Wadher S. J.

ANTI-TUBERCULAR ACTIVITY OF SYNTHESIZED NOVEL 2,5-DISUBSTITUTED-1,3,4-OXADIAZOLE DERIVATIVES

PAGE 40-44
A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromati...
Ega D., Attari Z., Mudgal J., Bairy I., Vishnuprasad S., Nampurath G. K.*
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