Table of Contents

March  2020

  • Volume 57
  • Issue 3
  • Page Nos. 80

Guest Editorial

COVID-19: NEW PARADIGMS FOR DISEASE MANAGEMENT

PAGE 5-6

Dr. Vandana B. Patravale is currently a Professor of Pharmaceutics at the Institute of Chemical Technology, Mumbai, India. Her areas of research include development of nano-carriers with major emphasis on malaria, cancer and neurodegenerative disorders; medical device development, nano-diagnostic...

Dr. Vandana B. Patravale

Institute of Chemical Technology, Mumbai,

Review Article

RESEALED ERYTHROCYTES: A PROMISING APPROACH TO ENHANCE EFFICACY OF ANTICANCER DRUGS

PAGE 9-20

Targeted drug delivery system is a potential drug delivery system which delivers the drug to particular organ of interest only. This improves the therapeutic efficacy of the treatment by reducing the side effects of drug which are required in case of anticancer drugs. Erythrocytes have been the m...

Anuradha Chivatea*, Prathibha Salvea, Rajendra Doijadb and Niranjan Chivatec

Original Research Articles

DESIGN, SYNTHESIS OF SCHIFF BASE CIPROPFLOXACIN-VANILLIN DERAVATIVES OF POTENT BACTERIAL DNA GYRASE INHIBITOR

PAGE 21-26

A series of Schiff base ciprofloxacin hydrazones with vanillin analogues were designed and validated for druggability properties by advanced computational tools, from which two shortlisted compounds were synthesized and characterized by different spectral studies. These compounds were used agains...

Swain Sudhansu Sekhara, Sahoo Chita Ranjana,b, Sahoo Jyotirmayac, Padhy Rabindra Nathb, Ravi Kumar B. V. V.d and Paidesetty Sudhir Kumara*

EXTRACT OF WITHANIA SOMNIFERA ATTENUATES TIBIAL AND SURAL TRANSECTION INDUCED NEUROPATHIC PAIN

PAGE 27-36

Neuropathic pain can result from nerve injury, complication of diabetes, HIV infection and cancer. There are no defined guidelines for treatment and available treatments have often undesirable side effects. Hence, there is a adire need to develop treatment strategies which will be safe, effective...

Joshi Tanmayee Amita and Tatke Pratima Aruna*

CHEMOMETRICS ASSISTED SPECTROSCOPIC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS DETERMINATION OF SOFOSBUVIR AND DACLATASVIR DIHYDROCHLORIDE IN TABLET FORMULATION

PAGE 37-46

Four chemometric methods, namely Classical Least Square (CLS), Inverse Least Square (ILS), Partial Least Square (PLS) and Principal Component Regression (PCR), were developed for the simultaneous estimation of sofosbuvir and daclatasvir dihydrochloride in tablet formulation. Full factorial design...

Rathod Sapna M.a*and Patel Paresh U.b

 

EXPLORING THE POTENTIAL OF ORODISPERSIBLE TABLET OF ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE DRUG COMBINATION

PAGE 47-54

The objective of the present work was to formulate and evaluate orodispersible tablets of enalapril maleate and hydrochlorothiazide combination to overcome the shortcomings of conventional dosage forms and improve patient compliance. Eleven formulations were prepared by wet granulation method usi...

Ammanage Anand Shripala, Patil Yojana Dadasahebb, Saboji Jagadish Kamalanathc Kempwade Amolkumar Ashok*d and Hiremath Ravindra Durdundayyae

A VALIDATED METHOD FOR QUANTITATION OF PREGABALIN AND METHYLCOBALAMIN USING DIFF USE REFLECTANCE FTIR SPECTROSCOPY IN BULK AND COMBINED TABLET DOSAGE FORM

PAGE 55-61

A Simple, accurate precise and validated FTIR method was developed for the determination ofpregabalin (PRG) and methylcobalamin (MCA) in bulk as well as in tablet dosage form. The drug was analyzed by FTIR spectrophotometry with DRIFT sampling technique. wavenumb...

Dange Shital Shrirang*a, Kalyankar Tukaram Mohanraob, Adhav Satishb and Anita Kowthalamd

DEVELOPMENT AND VALIDATION OF NOVEL STABILITY INDICATING RP-HPLC METHOD FOR QUANTIFICATION OF TOLVAPTAN IN BULK AND PHARMACEUTICAL DOSAGE FORM

PAGE 62-68

Specific stability-indicating reversed-phase high performance liquid chromatography (HPLC) method has been developed and validated for the quantification of tolvaptan in bulk drug and pharmaceutical dosage form. The optimized conditions for the developed HPLC method are; Inertil ODS-3V column (15...

Noorbasha Khaleela* and S k. Abdul Rahamanb

Short Notes

RP - HPLC METHOD FOR DETERMINATION OF MEBEVERINE HYDROCHLORIDE IN DOSAGE FORMS EMPLOYING MS COMPATIBLE BUFF ERS

PAGE 69-72

A simple, precise, rapid, accurate and economic reverse phase high performance liquid chromatographic method has been developed for the estimation of mebeverine hydrochloride in bulk and tablet dosage form. The separation was achieved by using kinetex column C18 (150×4.6mm, 5µ) and 15mM ammoniu...

Marella Vijaya Lakshmia*, M.Pavania and Garikapati Devala Raoa

Prevention of apparent adiposity by fractions of distilled cow urine: a non-invasive approach

PAGE 73-78

Owing to the multifactorial pathological conditions management of obesity is a challenging problem. finding an effective and safe remedy is a huge area of interest for many scientists and healthcare professionals in the field of biomedicine. There is a traditional claim that fresh cow urine and i...

Hatware Ketana*, Sharma Sanjaya, Deshpande Ashwinia, Patil Kirana, Karri Sravania and Gautam Rupeshb

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