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More than 100 years before India was recognised as the “Generic Capital” or “Pharmacy of the World, India was acclaimed for the “Materia Medica” and the extensive research on natural products by Sir Col. Dr. Ram Nath Chopra, the father of Indian Pharmacology. In fac...

Hydrophobic ion-pairing (HIP) complexation technique has been displayed to modify the physicochemical properties, solubility, oral absorption, bioavailability, and the lipophilicity of an ionic drug in the lipid phase. This could affect a higher permeation through biological membranes. HIP comple...

A new series of piperazine-1, 3, 4-oxadiazole deviatives were synthesized by the condensation of 1, 3, 4-thidaizole with substituted piperazine, in the presence of N, N-diisopropylethylamine. The structures were confirmed by IR, 1H NMR, 13C NMR and Mass spectroscopy. All the precursors were scree...

Radioprotector is the prime antidote to radiation injury. The desire to search an ideal radioprotector led us to explore natural sources. Bamboo species are known for theirimmense medicinal potential such as antioxidant, anti-inflammatory, anti-cancer, immunomodulatory activities and are enriched...

Present work focused on thiolation for enhancing the mucoadhesive potential of Gum kondagogu (GK). Thiolation of GK was done by esterification process with 80 % thioglycolic acid in presence of 7N HCl. Thiolated Gum kondagogu (ThioGK) was determined to possess 1.59 ±0.04 mmol of thiol groups/g o...

A simple, specific, precise and robust method for the estimation of emtricitabine, bictegravir and tenofovir alafenamide in the presence of impurities was developed and validated. The separation was performed on Aquity UPLC system with SB C8 50 x 2.1 mm, 1.7μ column under isocratic elution mode....

A simple, cost effective, UV-VIS spectrophotometric method for analysis of elvitegravir (EVG) in the presence of plasma was developed to facilitate the assessment of clinical samples or as a routine alternative tool in drug quality control laboratories for quantitative estimation of EVG. The pres...

The aim of this research work was to create compelling strategy for biosurfactant generation by waste potato peels and pulp utilizing mutated B.subtilis DDU20161. Major parameters like creation of medium, fomentation, and pH were kept up in the investigation. The ideal biosurfactant yield by acet...

Cognitive impairment is one of the major problems associated with antiepileptic drugs. Phenytoin is one of the widely used anticonvulsant drugs, but it adversely affects learning and memory on prolonged use due to generation of reactive oxygen species. Metformin promotes neurogenesis, enhances sp...

Chromatography is the procedure for analysing a multicomponent mixture of trace, minor or major constituent by separaationinto its individual fractions.For the analytical determination of sildenafil in pharmaceutical dosages forms an expeditious & sensitive RP-HPLC method is described.The mob...

The genus Tanacetum L. belongs to the Asteraceae family and is one of the most important medicinal group that contains 26 species in Iran, 12 of them being endemic. Tanacetum pinnatum Boiss. grows wild in Iran. This paper reports the essential oil composition of T. pinnatum population in 3 provin...